找到约 15 条结果

文章 hmmsearch搜索蛋白保守结构域结果说明

...三对对于一些不可靠的结果差异会大一些,模糊区域; The domain hits table In protein search programs, the --domtblout option produces the domain hits table. There is one line for each domain. There may be more than one domain per sequence. The domain table has 22 whitespacedel...

文章 利用NCBI当中的CD-search工具预测基因的保守结构域

...non-specific hits) and domain model scope (superfamilies, multi-domains). They can be seen in both the Concise display and Full display, except for non-specific hits, which are shown only in the Full Display.PSSM-IDA PSSM ID is the unique identifier for a domain model's position-specific scor...

文章 z-Transform数据得到z-score方法公式

z-Transform Sometimes one has the problem to make two samples comparable, i.e. to compare measured values of a sample with respect to their (relative) position in the distribution. An often used aid is the z-transform which converts the values of a sample into z-scores: with zi ... z-transfo...

文章 细胞焦亡、铁死亡及铜死亡等基因集

... website (http://www.autophagy.lu/clustering/index.html, last update time: 202112-3), and a total of 206 ARGs were obtained.We extracted 232 autophagy-related genes from the human autophagy database (HADb, http://autophagy.lu/clustering/index.html). 焦亡(Pyroptosis) 相关基因: We identi...

问题 Blast2go本地化过程中,运行官方文件b2g4pipe_v2.5.zip中“runPipeExample.sh“报错“The host did not accept the connection within timeout of 60000 ms;”

...整导入,然而运行官方软件“sh runPipeExample.sh”时报错“The host did not accept the connection within timeout of 60000 ms;”,请问如何解决,希望详细点。 Prepare data for GoSlim. 8 Sequences send to preform GoSlim: goslim_generic.obo Error while generating GoSlim res...

文章 基因组版本 Primary 和 Alternate的区别

... useful by itself as it is fragmented and incomplete.https://lh3.github.io/2021/04/17/concepts-in-phased-assemblies

问题 请问为什么三个pca成分成为作为pca协变量控制群体结构对GWAS关联准确性的影响进行GLM和LLM时,识别到四个协变量,删除第一行截距后,仍旧识别到四个协变量,这是为什么啊

....txt -c /wtmp2/user049/yushiyan/pca/cpca_no1.txt -lm 1 -n 1 GEMMA 0.98.5 (2021-08-25) by Xiang Zhou, Pjotr Prins and team (C) 2012-2021 Reading Files ... **** INFO: no intercept term is found in the cvt file: a column of 1s is added. ## number of total individuals = 21 ## number of analyzed ind...

文章 基因家族的定义和形成方式(加倍与扩张)

...yza sativa: a history of duplications. PLoS Biol. 2005, 3 (2): e38-10.1371/journal.pbio.0030038.[3] Ramamoorthy R, Jiang SY, Kumar N, Venkatesh PN, Ramachandran S: A comprehensive transcriptional profiling of the WRKY gene family in rice under various abiotic and phytohormone treatments. Plant Cell ...

文章 GWAS,TWAS,eQTL,EWAS等的关系定义

...D: Arabidopsis thaliana multi-omics association database, Nucleic Acids Research, Volume 49, Issue D1, 8 January 2021, Pages D1445–D1451, https://doi.org/10.1093/nar/gkaa1042

文章 lasso_cox.r lasso_cox 模型优化分析

...n Paths for Cox’s Proportional Hazards Model via Coordinate Descent.” Journal of Statistical Software, Articles 39 (5): 113. https://doi.org/10.18637/jss.v039.i05.Therneau, Terry M., and Patricia M. Grambsch. 2000. Modeling survival data: extending the Cox model. Springer.Tibshirani R (19...

问题 fastqc质控时报错,提示Ran out of data in the middle of a fastq entry.是什么问题?

问题 转录组KEGG富集分析出现问题。

...b.io/software/clusterProfiler   If you use clusterProfiler in published research, please cite: Guangchuang Yu, Li-Gen Wang, Yanyan Han, Qing-Yu He. clusterProfiler: an R package for comparing biological themes among gene clusters. OMICS: A Journal of Integrative Biology. 2012, 16(5):284-287. DO...

文章 bedtools统计序列中碱基含量

...: Tool:    bedtools nuc (aka nucBed)Version: v2.25.0Summary: Profiles the nucleotide content of intervals in a fasta file.Usage:   bedtools nuc [OPTIONS] -fi <fasta> -bed <bed/gff/vcf>Options:        -fi     Input FASTA file        -bed    BED/GFF/VCF file of ranges to ...

问题 差异基因用p-vaule筛选可以吗?

...s were determined using p-value < 0.05 and fold change ≥ 1.5. What is the rationale behind using pvalues instead of adjusted pvalues/FDR. Multiple testing correction is a very crucial aspect of RNA-Seq data analysis since there are thousands of genes being tested and using p values instead of a...

文章 STRING蛋白互作网络图绘制及子网络分析

...身影,因此绘制一幅精美的互作网络图十分重要。 例如2021年5月发表在Mol Ther Nucleic Acids中的文献《Comprehensive analysis to identify DLEU2L/TAOK1 axis as a prognostic biomarker in hepatocellular carcinoma》,影响因子8.89。作者首先分析PTEN相关的差异...