找到约 15 条结果

文章 GWAS分析哪个模型最优

...并绘制QQ图。CW trait (H = 80% 下图A) 关联结果看, ANOVA, GLM, and SUPER假阳性高;MLM, CMLM, and ECMLM这几个模型只是尾部少量SNP翘起说明假阳性减少但可能存在假阴性,因为尾部翘起的点较少。而FarmCPU 尾部高高翘起而且多说明这个模型假...

文章 筛选编码蛋白的CDS序列

...args.out_dir)    dout=os.path.abspath(args.out_dir)count=0total=0output_handle = open(dout+'/'+args.prefix+'.fa', "w")for rec in SeqIO.parse(args.fasta, "fasta"):    seq=str(rec.seq)    #seq=seq.upper()    total+=1    if(len(seq)>=args.len and re.search("^ATG",seq,re.I) and len(seq)%3==...

文章 pip报错

...WARNING: Running pip as the 'root' user can result in broken permissions and conflicting behaviour with the system package manager. It is recommended to use a virtual environment instead: https://pip.pypa.io/warnings/venv 以“root”用户运行pip可能导致权限中断,可以尝试使用虚...

文章 exp_immu_cor_plot.r 基因表达量与免疫侵润相关性绘图分析

...e/1488 optional arguments: -h, --help show this help message and exit -e expset, --expset expset set event column name [required] -i immu, --immu immu input data file path[required] -m method, --method method a character string ind...

文章 multi_cox.r 基因表达量做多因素cox分析

...onoptional arguments:  -h, --help            show this help message and exit  -i data, --data data  input data file path[required]  -t time, --time time  set suvival time column name [required]  -e event, --event event                        set event column name must 0 or 1 ...

文章 基因家族的定义和形成方式(加倍与扩张)

...f several similar genes, formed by duplication of a single original gene, and generally with similar biochemical functions.  基因家族的形成方式(加倍与扩张): 1.染色体組多倍化( Whole genome duplication or  polyploidization):大部分植物都经历过古老的全...

问题 安装github上的包报错:

...) Using github PAT from envvar GITHUB_PAT. Use `gitcreds::gitcreds_set()` and unset GITHUB_PAT in .Renviron (or elsewhere) if you want to use the more secure git credential store instead. Error: Failed to install 'unknown package' from GitHub:   HTTP error 401.   Bad credentials   Rate lim...

问题 TCGA的RNA-seq count annotation过滤,有些不知道是否需要删除

...ion:General:This subject was duplicated by TCGA-24-0981; 0981 was redacted and this one retained 2. patient_annotation:Notification:Item in special subset:This is part of the ovarian triplet set. 3. aliquot_annotation:CenterNotification:Item flagged DNU:QC Warning- Expression quality metrics ...

问题 TCGAbiolinks包

你好,我遇到了跟你一样的问题Downloading genome information (try:0) Using: Human genes (GRCh38.p13) 错误: $ operator is invalid for atomic vectors 请问怎么更新R包解决呢?

问题 Error running system command:

...ant这几个大小为0,运行提示如下NOTICE: Running with system command <convert2annovar.pl  -includeinfo -allsample -withfreq -format vcf4 /work/my_reseq/4.snp_indel/all.clean.snp.vcf.gz > /work/my_reseq/5.var_ann/snp.avinput> NOTICE: Finished reading 5099177 lines from VCF file ...

文章 IF=8.78|非肿瘤数据挖掘思路(GWAS Catalog)

...表型称为“主要表型”,第二个表型作为“条件表型”。Andreassen等己经应用这种方法,并成功发现了与几对相关性状相关的多效新位点/基因。目前,这种方法成功地应用到精神分裂症和双相情感障碍、精神分裂症和心血管疾...

问题 如何用荧光定量数据绘制热图?

...n different tissues as determined by qRT-PCR. There were three biological and three technicalreplicates performed for each sample. The relative expression levelswere evaluated by 2-ΔΔCT. GraphPad software was used for the statistical analyses. 作者是用的2-ΔΔCT的方法做的数据分析...

文章 svg2xxx运行报错

...ava.lang.UnsupportedOperationException: The Security Manager is deprecated and will be removed in a future release at java.base/java.lang.System.setSecurityManager(System.java:425) at org.apache.batik.util.ApplicationSecurityEnforcer.installSecurityManager(Unknown Source) at ...

文章 快速高效KM生存曲线绘制-脚本使用

...--metadata metadata input the path to the clinical information file containing survival data[required] --surv_cut Whether to group by surv_cutpoint function[optional,default:False] --median_cut Whether to...

文章 IF=3.47|非肿瘤-眼部老年黄斑变性ceRNA文章思路

...en C. circRNA-miRNA-mRNA network in age-related macular degeneration: From construction to identification. Exp Eye Res. 2021 Feb;203:108427. doi: 10.1016/j.exer.2020.108427. Epub 2020 Dec 29. PMID: 33383027. 延伸阅读 GEO数据库挖掘—WGCNA鉴定骨肉瘤转移相关基因GEO、TCGA多数...