找到约 15 条结果

文章 Nature Medicine同期8篇论文，聚焦人工智能在医学领域的应用

...BioWorld列举并介绍了这8篇论文： 1 High-performance medicine: the convergence of human and artificial intelligence 高效医学：人类与智能的融合 作者：Eric J. Topol；单位：Scripps研究所 通过在所有部门中使用标记的大数据以及显著增强的计算...

问题 Bioconductor包安装时出现警告，导致最后出来的图片部分缺失

...or.org/packages/3.2/bioc/src/contrib/AnnotationDbi_1.32.3.tar.gz' Content type 'application/x-gzip' length 4268480 bytes (4.1 MB) ================================================== downloaded 4.1 MB trying URL 'https://bioconductor.org/packages/3.2/bioc/src/contrib/annotate_1.48.0.tar.gz' Con...

文章 胃癌免疫侵润预后Signature数据挖掘-4.8分SCI思路解析

...Xena 网站下载得到用于预测模型构建；GEO数据库中 GSE62254 and GSE29274数据集用于模型验证。免疫侵润分析方法：ESTIMATE （R包）和 CIBERSORT （在线工具），ssGSEA（GSVA)。 预后signature查找： 免疫评分聚类区分免疫亚型 根据ssGSEA 评估...

文章 单细胞RNA速率（RNA velocity）分析结果解读

...速率流线图准确地描绘了细胞分化轨迹。 velocity length: the speed or rate of differentiation is given by the length of the velocity vector.velocity confidence:  the coherence of the vector field (i.e., how a velocity vector correlates with its neighboring velocities) provides a mea...

文章 plink 软件core dumped报错

...variants loaded from .bim file.9696 missing IDs set.114 people (0 males, 0 females, 114 ambiguous) loaded from .fam.Ambiguous sex IDs written to LDfiltered.nosex .--extract: 435 variants remaining.Using 1 thread (no multithreaded calculations invoked.Before main variant filters, 114 founders and 0 n...

文章 GATK|Timeout of 30000 milliseconds was reached while trying to acquire a lock on file raw.vcf.tmp.idx.

...是空的。 然后再在命令行中添加-disable_auto_index_creation_and_locking_when_reading_rods 这个参数。并运行命令行

文章 Orthology 定义

...or example, when reconstructing a phylogeny from amino acid sequences that the proteins be homologous. [. . . ] there should be two subclasses of homology. Where the homology is the result of gene duplication so that both copies have descended side by side during the history of an organism (for exam...

文章 GWAS分析哪个模型最优

...并绘制QQ图。CW trait (H = 80% 下图A) 关联结果看, ANOVA, GLM, and SUPER假阳性高；MLM, CMLM, and ECMLM这几个模型只是尾部少量SNP翘起说明假阳性减少但可能存在假阴性，因为尾部翘起的点较少。而FarmCPU 尾部高高翘起而且多说明这个模型假...

问题 下载甲基化数据时找不到样本类型，

...        platform = platform,+                       sample.type = sample_type)--------------------------------------o GDCquery: Searching in GDC database--------------------------------------Genome of reference: hg38|tissue.code |shortLetterCode |tissue.definition             ...

问题 老师，请问sample type出现这种情况怎么解决，麻烦老师解惑一下，谢谢啦。

...Methylation"> platform <- "Illumina Human Methylation 27"> sample_type <- "Primary solid Tumor" > legacy <- FALSE> # 设置工作目录（输出目录）> setwd(work_dir)> DataDirectory <- paste0(work_dir,"/GDC/",gsub("-","_",tcga_project))> FileNameData <- paste...

问题 16S 差异比较使用compare_errorbar.r的时候报错

...trieve the full column specification for this data. ℹ Specify the column types or set `show_col_types = FALSE` to quiet this message. Error in `select()`: ! Can't subset columns with `metaData[, 1, drop = T]`. ✖ Can't convert from `metaData[, 1, drop = T]` <double> to <integer> due t...

问题 blastp提示ensemble中提取的序列文件不对

...ameters due to an invalid query sequence or its translation. Please verify the query sequence(s) and/or filtering options 已去除序列中的终止子符号。 e.g： >ENST00000620518 ENSG00000081692  JMJD4 1:227732392-227735273(-) MDRETRALADSHFRGLGVDVPGVGQAPGRVAFVSEPGAFSYADFVRGFLLPNLPCVF...

文章 基因组组装GC 含量与深度图：

...lab.org/seurat/reference/dimplot')parser$add_argument( "-i", "--gc.table", type="character",required=T, default=NULL,help="input single Seurat obj in rds file [required]",metavar="filepath")parser$add_argument( "-d", "--depth.table", type="character",required=T, default=NULL,help="input single Seura...

问题 成功安装WGCNA包后，调用时报错

....tuna.tsinghua.edu.cn/CRAN/bin/windows/contrib/3.5/WGCNA_1.66.zip' Content type 'application/zip' length 3436551 bytes (3.3 MB) downloaded 3.3 MBpackage ‘WGCNA’ successfully unpacked and MD5 sums checkedThe downloaded binary packages are in C:\Users\NY\AppData\Local\Temp\RtmpYrZpG5\downloaded_p...

文章 16S扩增子测序后的PICRUSt预测功能分析原理

...便快捷，成本也更低。 2016年发表在微生态学旗舰期刊《TheISME Journal》的《Cigarettesmoking and the oral microbiome in a large study of American adults》[2]中，作者就通过PICRUSt预测了吸烟人群和未吸烟人群的口腔菌群，发现共有83个基因功能代...